Medical expert of the article
New publications
D-dimer analysis in pregnancy
Last reviewed: 05.07.2025
All iLive content is medically reviewed or fact checked to ensure as much factual accuracy as possible.
We have strict sourcing guidelines and only link to reputable media sites, academic research institutions and, whenever possible, medically peer reviewed studies. Note that the numbers in parentheses ([1], [2], etc.) are clickable links to these studies.
If you feel that any of our content is inaccurate, out-of-date, or otherwise questionable, please select it and press Ctrl + Enter.
It is recommended not to ignore the D-dimer analysis during pregnancy.
D-dimer refers to the products of fibrin lysis, which is part of the thrombus. The analysis allows you to find out whether there is a risk of accelerated thrombus formation in the expectant mother or not. Before taking blood, it is advisable not to consume liquids and food for at least 12 hours.
[ Who to contact?
Normal D-dimer levels for pregnant women
- 1st trimester – 750 ng/ml.
- 2nd trimester – 1000 ng/ml.
- 3rd trimester – no more than 1500 ng/ml.
Increased D-dimer during pregnancy
An increase in the level indicates an increased risk of blood clots, and this can be preceded by a number of diseases:
- Presence of diabetes mellitus.
- Presence of diseases of the urinary system.
- Confirmation of gestosis.
- Confirmation of infectious diseases.
- Presence of liver disease.
- Early placental abruption and risk of miscarriage.
D-dimer below normal during pregnancy
If D-dimer is significantly lower than the norm for pregnant women, this already indicates a decrease in blood clotting and the risk of bleeding incompatible with life. In such cases, hospitalization, consultation with a hematologist and a course of coagulants are required. It is especially important to conduct a D-dimer test immediately before childbirth, when the fact of blood loss is irrefutable and in case of complications, it will be necessary to provide quick assistance.