Sprays against alopecia

Although hair loss is associated with many causes, primarily of an immune and hormonal nature, a clinically proven spray against alopecia can be useful in the complex therapy of alopecia.

And indications for the use of the spray against alopecia include androgenic and focal alopecia in men and diffuse hair loss in women. Cosmetic products - aerosol products for hair care - is also designed to prevent hair loss.

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Pharmacodynamics

Spray from alopecia Generolon (Rogaine) improves blood flow of hair bulbs due to the active substance minoxidil - a vasodilator (pyrimidinediamine derivative) against increased blood pressure. As a result of the action of this substance, the metabolism in the follicles is activated and the anagenic phase of the hair (growth phase) is prolonged. As noted in the official instructions to the drug, the effectiveness of its use is higher in the initial stage of alopecia. And Generolon is more effective as a baldness spray for women. However, hair growth is restored and continues only if the drugs are used continuously.

The pharmacodynamics of the Alopel spray is based on the complex effects of the extracts of large burdock roots and narrow-leaved sophora, mountain arnica grass, red clover, nettle, rosemary, sage, ivy, green tea leaves (Camelia Sinensis), pine, chamomile flowers, nasturtium, lemon peel. Also included in the product are hydrogenated castor oil, D-panthenol, camphor, sodium hyaluronate, biotin (vitamin H), and acetyl tetrapeptide complex. Feeding the epithelial membrane of the hair roots, the preparation Alopel helps restore their growth.

In the Eksiderm spray, recommended for damaged hair and hair loss, include extracts: aloe vera, coltsfoot, burdock, hops, birch leaves, nettles, St. John's wort, juniper, chamomile, oak, clover, plantain, sage, D-panthenol , vitamins (A, C, E, B5, B6, PP).

Pharmacokinetics

Up to 2% of the active ingredient of minoxidil, which is part of the Spray from Alopecia Genololon (Regein), is absorbed into the bloodstream, reaching a maximum concentration 5.5-6 hours after application of the spray to the scalp. About 38% of minoxidil binds to plasma proteins.

About 60% of the minoxidil that enters the blood is transformed into the liver; the average term for excretion of the drug (through the kidneys and intestines) is 40-44 hours, and after stopping the use of spray Generolon (Regein) - four days.

The pharmacokinetics of the Alopel spray and the Exciderm in the descriptions of these agents are not given.

Names of Sprays from Alopecia

The main names for the baldness sprays, which are pharmaceuticals: Regein (Aerosol-Service AG, Switzerland) and its synonym for Generolon (2% and 5% spray produced by Belupo , Croatia ), and Alopel (produced by Catalysis, SL, Spain).

In addition, there are hair growth activating Eksiderm and advertised as a hair loss spray from Hair megaspray and a spray from balding Ultra hair system. They are not medicines. Moreover, the products for strengthening hair Ultra hair system and Hair megaspray produced in the Russian Federation are realized only through the Internet.

Method of application and dose of the spray against alopecia

All sprays from baldness are applied externally. Generolon (Regein) is applied to the dry skin of the scalp: a one-time dose is 1 ml, which corresponds to seven clicks on the spray nozzle.

For men it is recommended to use the drug twice a day (without washing your head after applying the spray), women - once.

According to the information of the official instructions, the first signs of regaining hair growth can be noticed after 2-3-4 months of using this remedy. Hair will begin to fall out again if the use of Generalolon (Regain) ceases.

Spray Alopel should be applied to the areas devoid of hair, once or twice a day (the second time - at night), each time conducting a gentle scalp massage for 30-40 seconds. The method of application of the Excidram is similar.

Overdose of the spray from alopecia Generolon (Regein) causes a more intense manifestation of side effects (lowering blood pressure, edema, tachycardia).

Hair Loss Sprays Hair megaspray and Ultra hair system

As already mentioned above, the Ultra Hair System (Dr. Lorel), which has failed to establish the manufacturer, contains oils (burdock, coconut, argan, cinnamon) vitamins (A and E) and extracts of the root of the aura and chamomile flowers. This tool for the care of weakened dry hair with the tips of the tips, which are positioned in the market of similar products as an activator of hair growth. It is noteworthy that the so-called Ultra Hair System balding spray is recommended to be applied not only to the hair roots, but also to the hair itself.

Means with the name of the spray from hair loss Hair megaspray, judging by the differences in the components of the components, at least two, and both produced in Russia. Judging by the advertisement, Hair megaspray restores brittle, split and damaged hair, gives vitality and shine to dry hair, and also strengthens hair roots thanks to: burdock, argan, coconut, cinnamon and avocado oil; vitamins A and E; extracts of chamomile pharmacy, nettle and bitter pepper.

The second hair loss spray Hair megaspray contains: Evening primrose oil rich in linoleic acid (evening primrose); essential oil of black pepper and bay oil (from the seeds of the laurel of the American). These means are traded exclusively on the Internet, which gives good reasons (in the absence of information about their producers and the abundance of "rave reviews") to doubt the appropriateness of their acquisition and application.

Contraindications for use

Among the contraindications to the use of spray Generolon (Regein) note a hypersensitivity to minoxidil or other substances in the formulation; presence of wounds, scratches, scratching and other skin lesions of the scalp; dermatological pathology of the scalp; age is 18 years and over 65 years.

Alopel Male Alopecia Spray has no contraindications. And contra-indications of Spray Exiderm are skin diseases localized on the scalp.

The use of a spray against alopecia during pregnancy, particularly the drug Generolon (Regein), is contraindicated; when lactating, this agent is also not used.

Concerning the means of Alopel and the Exciter, information about the possibility of their use by pregnant and breast-feeding women is absent.

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Side effects

When using Spray Generolon (Regeyn), there may be side effects that are expressed by headache, skin itching, flushing and rashes, as well as a runny nose, a drop in blood pressure.

In some cases, swelling (lips, tongue, oropharyngeal tissues), dizziness, eye irritation, increased heart rate, shortness of breath, painful sensations behind the sternum can be observed. And on the scalp may appear peeling, blisters or ulceration.

Alopel Alopecia Spray has no side effects.

Interactions with other drugs

Means containing minoxidil, interact with other drugs:

• minoxidil is worse absorbed by the skin with simultaneous application of external means Acriderm, Betacorlan, Betacort, Betilol, Celestan, Supercorthen and others with synthetic GSK betamethasone.
• the absorption of minoxidil is increased if a cream against acne is used in parallel. Tretinoin or external preparations of Ditranol, Acrychim, Zignoderm and other creams with dithranol.

Optimal storage conditions for sprays assume a temperature of up to + 25 ° C. Shelf life of the spray Generalolon (Regaine, Rogaine) - 36 months; Alopel spray - 24 months; Exciterm - 12 months.