Nizoral Dandruff Shampoo

Dandruff is a problem familiar to many people. Noticeable, peeled particles of cornified skin can cover not only clothes, but also appear through the hair, which looks completely unaesthetic. In addition, dandruff is often accompanied by itchy, uncomfortable sensations, and regular shampooing does not lead to relief. In this situation, Nizoral shampoo for dandruff can help - it is a popular remedy in dermatology, which eliminates the main cause of the pathology - a fungal pathogen that causes all the signs of seborrheic dermatitis.[1]

Indications Nizoral for dandruff

One of the main indications for the use of Nizoral Dandruff Shampoo is the presence of a yeast-like fungus of Malassezia on the scalp. Excessive activity of the fungal pathogen leads to the development of painful disorders, including hyperkeratosis - enhanced cell division of the epidermal layer.

Dandruff, in particular, may be associated with hyperactivity of glandular secretion and changes in the composition of skin sebaceous secretions. Such reactions lead to a violation of local immunity, to the weakening of the protective function of the skin.

Dandruff can be the result of hormonal, neurogenic, immune processes in the body. Certain genetic factors, the effect of deep or frequent nervous stress, unhealthy diet and lifestyle, are not excluded. However, in the presence of concomitant factors, there is always the first underlying cause - a fungal infection that can be stopped using Nizoral shampoo. The study showed that shampoos containing the antifungal substance Nizoral were the most effective in combating the dandruff pathogens Malassezia furfur (Pityrosporum ovale).[2]

Release form

The composition of such a product as Nizoral shampoo from dandruff is represented by active and auxiliary ingredients. The main one is ketoconazole, an antifungal drug substance derived from imidazole that successfully cope with mycoses.

Auxiliary composition is presented:

• sodium lauryl sulfate;
• lauryl sulphosuccinatom dinataria;
• coconut oil fatty acid diethanolamide;
• collagen hydrolyzate;
• macrogom;
• sodium chloride;
• hydrochloric acid;
• imidova;
• sodium hydroxide;
• flavoring and tinting substances.

Nizoral shampoo can be packaged in plastic bottles of different capacities: the smallest of them - 25 ml, medium - 60 ml and more - 120 ml. In the pharmaceutical network antidandruff is positioned as an antifungal drug for local use.

Pharmacodynamics

Nizoral dandruff shampoo is both a prophylactic and therapeutic product with antiseborrheic and antifungal activity, which is successfully used to get rid of dandruff and other unpleasant symptoms (including with seborrheic form of dermatitis). As practice shows, even with frequent use Nizoral shampoo does not cause irritation of the skin, and the consistency of the drug is such that it allows you to easily and quickly process hair and scalp, which allows you to influence the problem as efficiently as possible.

Shampoo Nizoral dandruff demonstrates an active action against yeast fungi, dermatophytes, gram-positive coccal flora, higher fungi, certain dermatomycotic pathogens, dimorphic fungi, pathogens of systemic mycoses. The tool counteracts the growth and development of dermatophytes, is effective in the treatment of seborrheic eczema, pityriasis versicolor, dandruff, while not penetrating into the systemic circulation.

Pharmacokinetics

The concentration concentrations of the active ingredient in the study were so miserable that they were not determined in the blood serum when applied externally with Nizoral shampoo on the skin and scalp. The determination of this content was made possible only when applying the product over the entire surface of the body: the concentration in this case ranged from 11.2 to 33.3 ng per milliliter. Experts consider this indicator to be clinically insignificant or one that cannot affect any drug interactions. When using shampoo Nizoral in large quantities increases the likelihood of allergic processes.[3]

Details of the kinetic picture of the external use of Nizoral dandruff shampoo have not been studied.

Dosing and administration

For the treatment of dandruff in adults and children over the age of twelve, Nizoral shampoo is applied to the scalp and hair for about 4 minutes, foamed, and then washed off with warm water. The frequency of application of the funds - twice a week for ½-1 month.

For prophylactic purposes, the product is used according to the scheme once a week, or once every two weeks, alternating with conventional means for washing hair.

If any additional anti-dandruff remedies are used (creams, ointments, balms), then the possibility of combining them with Nizoral shampoo is discussed individually with a specialist.

Application for children

Negative effects of a systemic nature when using shampoo Nizoral from dandruff is not observed. However, specialists do not give a clear answer to the possibility of using this tool in pediatrics - primarily because of the lack of relevant research involving children. Therefore, it is officially considered that it is possible to use Nizoral for the treatment of dandruff in children from the age of 12 years. [6]If you want to use the tool before this age, you should consult with a specialist - in particular, with a pediatrician.

Use Nizoral for dandruff during pregnancy

Studying the possibility of penetration of the active component of Nizoral shampoo into the systemic circulation, the researchers were convinced of the absolute safety of this product. However, such studies with the participation of pregnant or lactating women have not yet been conducted, so experts cannot recommend the use of the drug during these periods. [4]It is not known whether there is a danger to the immediate course of pregnancy or to the health of the future baby.

However, the plasma concentration of the active ingredient in Nizoral shampoo was not detected after the usual daily use of the product by non-pregnant women. It can be assumed that during pregnancy the risks of a negative effect of the shampoo are practically reduced to zero. Given the above, it is allowed to use Nizoral dandruff for pregnant and lactating women, but specialist advice should also be mandatory.

Contraindications

Age up to 12 years, periods of pregnancy and lactation are relative contraindications to the use of Nizoral shampoo from dandruff. They are relative because in certain situations the doctor may allow both the pregnant woman and the small child to use the shampoo - for example, if it is not possible to use another remedy, and at the same time there is confidence in the safety of Nizoral.

As for unconditional contraindications, then they include individual hypersensitivity and allergic mood of the body to at least one ingredient of the shampoo.

Allergic reactions to date have become widespread throughout the world, and have a tendency to further growth. Allergen can be almost any substance - including part of the hygienic treatment-and-prophylactic products, such as shampoo Nizoral for dandruff. In this case, the first procedure with shampoo can go smoothly, and an allergic reaction is already detected from the second application. If the unpleasant symptoms of allergies still appear, then you need to stop using the product and consult a specialist. In the future, it will be necessary to carefully study the composition of dandruff shampoos, in order not to choose a product with a potential allergen again.

Side effects Nizoral for dandruff

Adverse events associated with the use of Nizoral dandruff shampoo on the scalp are extremely rare - in about 1% of cases. And some of these symptoms occur more often than others, and some - very rarely, or even recorded in isolated cases. But everyone needs to be aware of such likely manifestations, first of all for safety reasons for their own health.

We are talking about such side effects:

• inflammatory processes in the hair follicles - folliculitis;
• the formation of hypersensitivity to dandruff shampoo ingredients;
• temporary change in taste;
• increased tearing, conjunctivitis;
• hair loss, dry skin or hair, changing the quality of hair;
• sensation of skin irritation, the appearance of rashes (including acne);
• contact dermatitis, changing the color of the hair;
• reddening of the skin, itching;
• the formation of pustules, allergic processes.

If any of the listed symptoms appear, it is necessary to stop contact with the agent and consult a specialist. [5]

Overdose

During the use of Nizoral shampoo from dandruff, there were no cases of overdose, since the drug has no systemic effect and is applied only externally.

If the remedy is accidentally or intentionally swallowed, then it is necessary to consult a doctor for symptomatic and supportive treatment. To provoke a gag reflex, or to flush the stomach is strictly prohibited, in order to avoid foaming and aspiration. It is recommended to take any sorbent, and subsequently - a laxative drug.

If the shampoo was taken by the child inside, then a request for medical care must necessarily follow.

Interactions with other drugs

Specialists have not established a single drug interaction shampoo Nizoral dandruff. Since the product has no systemic effect, it can be combined with any medication for internal use.

The external combination of several dandruff preparations at once should be negotiated with a specialist, as this can lead to unforeseen and unpleasant consequences - for example, excessive dry skin, hair loss, etc.

Storage conditions

Shampoo Nizoral dandruff is allowed to keep under normal conditions, adhering to a temperature range from +8 to + 25 ° C. Do not allow children to storage places washing hygienic therapeutic and prophylactic products.

Not suitable for storing shampoos places close to heaters, radiators, as well as areas of direct sunlight. Optimally, if such a place is cool, well ventilated.

Shelf life

Nizoral dandruff shampoo is allowed to be used for three years from the date of production: the release date is always indicated directly on the bottle with the product.

Analogs

Nizoral is not the only dandruff shampoo based on the therapeutic effect of ketoconazole. Other hygienic cleaning products have a similar composition and effectiveness:

• Dermazole Shampoo;
• shampoo Kenazole;
• Ketozoral-Darnitsa;
• shampoo orazol;
• Perhotal;
• Ebersept.

Keto shampoo plus has a similar effect. However, ketoconazole in this product is enhanced by another active ingredient - zinc pyrithione, which makes the product even more effective.[7], [8]

Reviews

Such a common phenomenon as dandruff is mainly associated with a fungal infection, in which the cell division mechanism is knocked down, the horny layer thickens, itching appears, and the skin begins to peel off excessively.