It is worth admitting that it sounds rather paradoxical, but the question "how to gain weight?" is as relevant for some as the question of losing weight is for others. Excessive thinness is the same problem as obesity.
Sex hormone binding globulin is a serum glycoprotein that, by binding to sex steroids (testosterone, estradiol, progesterone, etc.), regulates their biological activity.
Of the estrogens that combine estradiol, estriol and estrone, the most active and significant for us is the first one, it is into this that excess testosterone in peripheral tissues (especially in the fatty layer and liver) tends to be converted.
Part of the free testosterone in some target cells, under the influence of the enzyme 5-alpha-reductase (type 1 or 2), is converted into dihydrotestosterone (DHT), and part into the female sex hormone estradiol (this conversion occurs under the influence of enzymes with the general name aromatase).
Testosterone is a male sex hormone produced in the testicles of men. To be more specific, it is produced by the so-called Leydig cells, a collection of these cells is also called the pubertal gland.
Let's introduce, to begin with, several concepts, without familiarization with which further consideration of the section will be very, very difficult. Don't be afraid - no special knowledge will be required from you.
Like any communication network, the endocrine system includes signal sources, signals themselves, and signal receivers. In this case, these are cells that produce hormones, the hormones themselves, and their receptors.
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