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Can a nursing mom take Dopegit?
Last reviewed: 07.06.2024
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Drug with hypotensive properties from the pharmacological group of central α2-adrenostimulants. Reduces heart rate, decreases total peripheral vascular resistance. Reduces tissue concentration of dopamine, epinephrine and serotonin, suppresses plasma renin activity. Increases renal blood flow.
4-6 hours after oral administration leads to maximum reduction of blood pressure, which persists for 1-2 days. About 50% of the administered dose is absorbed from the digestive tract and metabolized in the GI mucosa. Maximum concentration in blood plasma is observed in 2-6 hours, which corresponds to the onset of hypotensive effect. Active components penetrate the CNS through the blood-brain barrier. Excreted by the kidneys with urine.
- Indications for use: arterial hypertension of moderate and mild severity. The drug is taken orally at 250 mg before bedtime with further dose adjustment. The duration of therapy is determined by the attending physician.
- Side effects: drowsiness, parkinsonism, paresthesias, dizziness and headaches, peripheral edema, bradycardia, heart failure, upper body hyperemia. Dryness of oral mucosa, nausea, vomiting, diarrhea, colitis, arthralgia, myalgia, decreased libido, febrile state, allergic reactions.
- Contraindications: intolerance to the drug components, acute hepatitis, hemolytic anemia, renal/liver failure, liver cirrhosis, systemic lesions of connective tissue, parkinsonism, depression, acute myocardial infarction.
- Overdose: arterial hypotension, bradycardia, weakness and drowsiness, diarrhea, vomiting, headache and dizziness, intestinal atony. Treatment is indicated by gastric lavage and administration of sympathomimetics if necessary.
Dopegit in breastfeeding and pregnancy is allowed only by doctor's prescription. The dosage for a nursing mother is 250 mg twice a day. The drug penetrates into the systemic bloodstream and is excreted with milk. Before starting treatment, the infant should be transferred to artificial nutrition or make a reserve of decanted milk. Lactation is restored after the end of the course of therapy.
Form of release: 250 mg tablets of 50 pieces in a bottle.