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Biorevitalization of the face with hyaluronic acid
Last reviewed: 06.07.2025

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At the moment, hyaluronic biorevitalization has become very popular in modern cosmetology. This procedure is aimed at skin rejuvenation. The word "biorevitalization" itself is translated from Latin as "natural renewal of life". The essence of this rejuvenation process is the intradermal introduction of hyaluronic acid obtained artificially.
Hyluronic acid (HA) is a natural hydrocolloid that is produced independently in our body. The functional task of HA is to provide the required amount of moisture in the cells of the skin. After all, it is the violation of the hydrobalance that leads to visible changes in the skin. These transformations are especially noticeable on the face, neck, décolleté area, and hands. The skin loses its natural elasticity, flexibility, and healthy color. Actually, hyaluronic biorevitalization helps to restore natural water exchange, thereby removing the visual signs of skin aging.
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Indications for the procedure
- The first symptoms of wrinkle formation (expression or gravitational).
- Sagging and puffy skin on exposed areas of the body (face, neck, arms).
- Signs of dehydration (dryness) of the skin.
- Face shape correction.
- Couperose (a pronounced “network” of small capillaries).
- Change in skin color for the worse (paleness, grayness due to the influence of bad habits).
- Preparing the skin for subsequent cosmetic rejuvenation procedures (e.g. medium or deep peeling).
- Damage to the integrity of the skin as a result of the influence of aggressive methods of rejuvenation and body correction (plastic surgery, liposuction).
- Increased functioning of the sebaceous glands, which results in increased oiliness of the skin, acne and enlarged pores.
- Melasma, pigment spots.
- Preventing skin aging.
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Preparation
All preparation for hyaluronic biorevitalization consists of the following actions, which are carried out 4-5 days before the start of the process:
- Consult a therapist and dermatologist to avoid contraindications to biorevitalization.
- Stop using drugs that reduce blood clotting activity (anticoagulants).
- Start a course of treatment with vitamin K aimed at preventing the occurrence of bruises.
- Avoid drinking alcoholic beverages and taking sleeping pills (to normalize the effectiveness of anesthetics).
- Together with the specialist who will perform the procedure, it is necessary to decide on the choice of the type of biorevitalization, the drug for administration and the device (in the case of hardware biorevitalization).
Technique hyaluronic biorevitalization
Natural hyaluronic acid (produced in the body naturally), depending on the length of the polysaccharide chain, is divided into low-molecular, medium-molecular and high-molecular. Low-molecular HA has an anti-inflammatory effect. Application in medicine - treatment procedures for burns, acne, herpes, psoriasis. For cosmetology purposes, it is used as separate components of creams, lotions and tonics. Medium-molecular hyaluronic acid inhibits the process of cell migration and reproduction. It is prescribed for eye diseases, arthritis. High-molecular HA has the ability to retain moisture in cells, and is also responsible for the normalization of all cellular processes in the body. It gives the skin elasticity and increases its protective functions. It is the high-molecular type of hyaluronic acid, which is manufactured industrially, that is currently used for biorevitalization.
Previously, high-molecular HA of animal origin was used for biorevitalization. It was obtained by separating enzymes of connective tissue of some parts of animals. Rooster combs and cattle eyes were mainly used. The method consisted of special fractionation with the extraction of lipids and proteins, purification, sedimentation and drying. Since this process required the use of high temperatures (from 85 to 100 degrees), high-molecular groups were destroyed and transformed into low-molecular ones. Therefore, the result after biorevitalization lasted for a very short time. In addition, there was a risk of allergies and inflammation due to possible protein residues in the finished substance. For this reason, at present, the type of hyaluronic acid of animal origin for biorevitalization is used with special caution.
Nowadays, hyaluronic acid obtained by biotechnological synthesis has become especially popular. The basis of HA biosynthesis are the cells of streptococcal bacteria cultured on a nutrient medium (in this case, wheat). The subsequent stages of the process are the isolation of hyaluronic acid, deep purification, precipitation and subsequent drying of the obtained substance. All stages of synthesis are carried out within the framework of strict rheological and bacteriological control. This guarantees the highest quality of the drug and compliance with mandatory chemical standards. Another important circumstance is the fact that hyaluronic acid obtained in this way is completely identical to HA produced naturally in the human body. Thus, its use for biorevitalization eliminates the possibility of allergies and inflammatory processes.
To perform hyaluronic biorevitalization in beauty salons, different types of HA are used: pure and diluted, cross-linked and non-cross-linked, low-molecular and high-molecular. The use of pure cross-linked low-molecular hyaluronic acid has proven itself very well.
I would like to mention hyaluronic acid with zinc separately. It is known that zinc has antioxidant and antibacterial properties. In addition, it regulates the process of cell regeneration and division.
What types of hyaluronic biorevitalization exist?
Due to the method of penetration of hyaluronic acid into the skin, this procedure is divided into two types: injection and non-injection.
Injectable hyaluronic biorevitalization of the face
The injection method of introducing HA involves the process of introducing the finished product into the tissues of the skin (or subcutaneously) using an ultra-thin needle. This procedure can be performed either manually (using a regular medical syringe) or by hardware (using special attachments that are put on the device for biorevitalization). The manual method of introduction, in contrast to the hardware method, is characterized by less aggressiveness. However, it requires special precision, attentiveness and high professional skills of the cosmetologist. For this reason, most patients who have chosen injection hyaluronic biorevitalization of the face prefer the hardware method.