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Contraindications to the use of hyaluronic acid

, medical expert
Last reviewed: 06.07.2025
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The method of artificial introduction of hyaluronic acid has recently found more and more adherents. But, having a structure similar to natural, there are still contraindications to the use of hyaluronic acid.

Hyaluronic acid is an invariable component of the human body, which is an indispensable participant in almost all physiological processes occurring in the human body. It is constantly synthesized and works in the epithelium, cartilaginous and connective tissues, nerve endings. Its reserves are replenished daily. Even having received severe sunburn once, the process of reproduction of this "hyaluronic acid" in the epidermis practically stops. The skin becomes flabby, losing its protective properties.

Contraindications to hyaluronic acid injections

Instructions for use of preparations based on Hyaluronic acid write about their full biological compatibility with the morphology and biology of the body. But in some cases the human body reacts to the effect of "foreign" hyaluronic acid with complications:

  • The body may react to this technique with facial asymmetry.
  • Necrotic ulcers may form at the injection site.
  • Allergic reactions to the administration of the drug are also common (if the patient has increased sensitivity to the components of the medication).
  • Provoking autoimmune diseases.
  • If the instructions are not followed, or in the case of an immune blockade, dense nodes may form under the skin.

Therefore, contraindications to hyaluronic acid injections still exist.

  • Any chronic disease in the acute stage.
  • Oncology at any stage of diagnosis or suspicion of cancer.
  • Pregnancy and lactation period.
  • Progressive inflammatory process.
  • Problems with hematopoiesis, disruptions in the blood clotting process.
  • Trauma and hematoma at the site of the intended injection.
  • New growth (nevi, papillomas, etc.) at the injection site.
  • Cosmetic procedures done the day before:
    • Photorejuvenation.
    • Laser resurfacing of epithelium.
    • Deep peeling of any skin type.
    • And others.
  • Predisposition to allergies.

Hyaluronic acid injections are one of the simplest methods of skin rejuvenation, it is quite minimally invasive (low probability of infection with parasitic microorganisms). But this does not mean that this method can be carried out in any beauty salon, trusting your body to a dubious specialist. A specialized clinic must have a license for this type of activity, and specialists must have the appropriate qualifications.

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Contraindications to hyaluronic acid injections

It is worth remembering that injections of Hyaluronic acid are associated with damage to the skin - this opens the "gate" for infection to enter the body. After the first injection, it is no longer possible to talk about the sterility of the procedure, since the needle no longer complies with the principle of asepsis. Even with local use, the effect of the drug on other body systems and its response cannot be ruled out. Therefore, even such a simple procedure has its own contraindications to injections of hyaluronic acid.

Injections should not be given if you have a history of:

  • Pregnancy and breastfeeding period.
  • Dermatological diseases.
  • Acute manifestation of chronic diseases.
  • Inflammation of the skin at the injection site or a general inflammatory process in the human body.
  • Autoimmune diseases.
  • Pathology of connective tissues.
  • Infectious tissue lesion.
  • In case of taking anticoagulants.
  • Allergic predisposition.
  • Cosmetic procedures (peeling, laser skin resurfacing, etc.) were performed. More than one month must have passed since these procedures.
  • Hypersensitivity of the skin.
  • Problems with blood clotting.

Contraindications to hyaluronic acid in tablets

No one can beg the importance of hyaluronic acid for the normal functioning of the body. The modern pharmaceutical market and the field of cosmetology are ready to offer their clients a huge selection of drugs created on the basis of Hyaluronic acid. Their choice is also wide in the form of tablets. The action of tablets is based on the same principles as when introducing a liquid consistency drug. The main thing is that the product is easily digestible, and, therefore, low molecular weight.

It is only necessary to note that when taken internally in the form of tablets, hyaluronic acid cannot act purposefully and spreads its effect to all systems and organs of the human body. Hence, the effect of their use is not so obvious and quick. After all, the acid primarily replenishes its deficiency in connective tissues, joints and only after that begins to work on the healing of the skin. It is possible to get the expected effect when taking tablets two to three months after the start of their use.

Based on the principle of action, this method of administration also has its own contraindications for hyaluronic acid in tablets.

  • Individual intolerance to the components of the drug.
  • An inflammatory process in the body, especially in the gastrointestinal tract.
  • You should not take the drug during pregnancy or lactation.
  • It is also contraindicated in cases of recent cosmetic procedures, such as cleansing and polishing of the skin and some others.
  • History of increased blood clotting.
  • Autoimmune diseases.
  • Gastritis and ulcerative diseases of the stomach and duodenum.
  • Acute forms of inflammatory and infectious diseases.

Therefore, before deciding on a "rejuvenating" procedure using Hyaluronic acid, you should consult your local doctor. Only he, knowing the health characteristics of his patient, can recommend or not such an effect on the body.

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Contraindications to hyaluronic acid for the face

The human dermis is 70% water, which corresponds to 15-18% of the volume of all water in the human body. Over time, when the aging process starts, the skin begins to dehydrate: the skin becomes flabby, dry, loses its elasticity and flexibility. The presence of a sufficient amount of Hyaluronic acid (its hygroscopic molecules) in the epidermis allows better retention of water in the skin and subcutaneous layers of the body. The skin of the face, neck and décolleté area is especially relevant for women.

But, before deciding on “rejuvenation”, it would be a good idea to familiarize yourself with the question of what are the contraindications to hyaluronic acid for the face.

  • Allergic predisposition.
  • Autoimmune diseases such as:
    • Endocrine system:
      • Diabetes mellitus.
      • Graves' disease.
      • Thyroid cancer.
    • Blood diseases.
    • Diseases of a neuralgic nature – multiple sclerosis, Guillain-Bare syndrome…
    • Gastrointestinal tract, liver:
      • Autoimmune pancreatitis.
      • Biliary cirrhosis of the liver.
      • Celiac disease is a digestive disorder caused by damage to the villi of the small intestine by certain foods.
      • Autoimmune hepatitis.
      • Ulcerative colitis.
    • Skin diseases:
      • Psoriasis.
      • Vitiligo.
      • Lupus erythematosus.
      • Erysipelas of the epidermis.
      • Chronic urticaria.
    • Kidney disease.
    • Heart disease:
      • Some types of myocarditis.
      • Rheumatoid fever.
    • Lung diseases:
      • Sarcoma.
      • Fibrosing alveolitis.
    • And many others.
  • Injuries, cuts, hematomas in the area that is planned to be subjected to the technique.

This method of rapid “rejuvenation” is becoming increasingly popular all over the world, but in order not to cause more harm to your body in the pursuit of beauty, it is better to first consult with qualified specialists and, if necessary, undergo examination and treatment.

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Contraindications to biorevitalization with hyaluronic acid

Biorevitalization (“natural revitalization”) is an innovative method of preventing aging, removing defects and correcting skin imperfections, thanks to the saturation of the superficial and deep layers of the epidermis with Hyaluronic acid.

The substance in question is a hydrocolloid, which is a component of the intercellular space. Hyaluronic acid is directly involved in the processes of nutrition and reproduction of cells. Without it, the synthesis of elastin and collagen, normal filling of the epidermal layers with water is impossible.

Like any medically oriented cosmetic procedures, this technique also has contraindications to biorevitalization with hyaluronic acid.

  • Infectious and inflammatory processes affecting the area of the proposed treatment. Injections into such infiltrates can stimulate the spread of infection or bacterial diseases throughout the patient's body. Therefore, it is necessary to cure the existing pathology first, and then proceed to rejuvenation.
  • Taking antibiotics.
  • Pregnancy and lactation. Due to the fact that there is no clinical research data on the effects of Hyaluronic acid on pregnant women, and based on the fact that during this period any outside intervention can negatively affect the health of the baby, any methods should be postponed to a later date.
  • Malignant neoplasms. Hyaluronic acid has a stimulating effect on the body's structures, without making a distinction between healthy and cancer cells.
  • Skin neoplasms (moles, nevi, papillomas). It is allowed to inject the preparation with Hyaluronic acid into areas adjacent to the neoplasm, but avoid damaging its integrity.
  • Diseases of the skin surfaces.
  • Exacerbation of chronic diseases. During this period, any cosmetic procedures are prohibited.
  • Individual intolerance to hyaluronic acid. Although it is similar in structure, biology and morphology to that found in the human body and is not an allergen, isolated cases of antagonism are still known.
  • Autoimmune diseases. Diseases of this nature cause the production of antibodies to one's own cells. That is, the immune system recognizes healthy cells of one's own body as foreign and seeks to destroy them. By influencing immune cells, Hyaluronic acid can provoke the activation of this process.
  • Keloid scars. A special type of neoplasms that penetrate into adjacent tissues. The growth and penetration of keloid scars, in most cases, begins a year after the wound has healed.
  • Hypertension.
  • Age up to 25 years.

The contraindications to biorevitalization with hyaluronic acid voiced above are not absolute. That is, only a doctor can recommend or not recommend the method. Therefore, when you are at his consultation, you need to voice in detail everything about your health. After all, there are rare diseases for which such procedures are not desirable, but they are not included in the prohibition list. This step will make it possible to get the greatest "rejuvenating" effect, reducing the risk of negative consequences to a minimum.

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Contraindications to laser biorevitalization with hyaluronic acid

Laser biorevitalization is an innovative medical and cosmetology technique performed using a light laser (which does not cause significant heating of tissues), delivering Hyaluronic acid through microchannels in the epidermis into the deep layers of the skin and subcutaneous tissue.

There are contraindications to laser biorevitalization with hyaluronic acid, as with any cosmetic “operation” of a medical nature.

  • The presence of skin diseases of bacterial, fungal or viral origin in the areas of expected exposure.
  • Pregnancy and breastfeeding period.
  • Tendency to epileptic seizures.
  • Differentiation of cancerous neoplasms in the body.
  • Increased production of thyroid secretions.
  • Allergic reaction to hyaluronic acid.
  • Tuberculous pulmonary disease.
  • Systemic blood diseases.
  • Skin defects in the form of scratches, wounds, cuts, bruises.
  • Advanced atherosclerosis of the cerebral vessels.
  • Rapid depletion of the body due to illness.
  • Decompensated diabetes mellitus.
  • Stage III hypertension.
  • Chronic cardiovascular diseases.
  • Psychoses that provoke outbreaks of hysteria and psychomotor agitation.
  • Hypersensitivity to laser radiation.
  • Significant number of moles and birthmarks in the area of impact.
  • Age up to 25 years.
  • Taking photosensitizing drugs that stimulate increased sensitivity of the human epidermis to light.
  • An infectious lesion of the body, accompanied by fever, chills, and high temperature.
  • The presence of piercings or tattoos in the area of the intended impact.

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Contraindications to lip augmentation with hyaluronic acid

Anyone wishing to acquire the plump lips of Angelina Jolie should not forget that there are contraindications to lip augmentation with hyaluronic acid.

  • You should not resort to rejuvenating procedures during pregnancy and breastfeeding. Since there are no clinical studies on the effect of "hyaluronic acid" on the child's body and the health of the mother herself.
  • It's not worth taking risks if you have problems with blood clotting.
  • It is better to wait until complete recovery in case of acute phases of chronic diseases or inflammatory processes in the patient's body.
  • If a woman has a history of autoimmune diseases, the use of Hyaluronic acid is contraindicated.
  • Skin infection.
  • If less than a month has passed since such cosmetic procedures as deep facial peeling, laser resurfacing.
  • The use of hyaluronic acid is strictly contraindicated if the patient has a history of connective tissue diseases.
  • Individual intolerance to the drug.
  • The “rejuvenating procedure” cannot be performed while taking anticoagulants.
  • There is also an age limit – 18 years.

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Contraindications to facial mesotherapy with hyaluronic acid

In most cases, the fair sex begins to notice the first signs of aging at the age of twenty-five. They try to compensate for the loss with various creams, scrubs, gels, but they cannot completely replenish the “lost youth”. Hyaluronic acid is a miracle product that can solve this problem.

Mesotherapy is one of the most effective methods of rejuvenation today. But there are also contraindications to mesotherapy of the face with hyaluronic acid.

  • Blood clotting disorder.
  • Pregnancy and breastfeeding.
  • Hypersensitivity to the components of the drug.
  • Tendency to allergic reactions.
  • Lesions of the skin area to be treated, wounds, bruises, hematomas, scratches.
  • Presence of neoplasms: nevi, papillomas, birthmarks.
  • Fear of injections (panic fear of injections).
  • Oncological diseases.
  • Severe form of diabetes mellitus.

Therefore, before deciding on a rejuvenation technique, it is worth consulting with licensed doctors who, after examining the patient’s medical history, will give reasonable recommendations regarding the rejuvenation procedure.

For many centuries, women have wanted to be young and beautiful. To meet her needs, medicine and cosmetology are progressively introducing more and more new methods of "rejuvenation", but this problem has not been completely solved. The use of procedures with Hyaluronic acid is the latest stage in cosmetology, but in the race for beauty, one should not forget about health. Who needs painful youth. Therefore, in order to minimize the possible occurrence of side effects, it is necessary to know the contraindications to the use of hyaluronic acid and resort to the services of only highly qualified specialists. This is the key to obtaining the desired result. Take care of yourself, listen to the advice of doctors and be healthy, beautiful and young!

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