At present, the following groups of medicines are used to treat various dermatoses in dermatocosmetology: antimicrobial, antifungal and antiviral agents, glucocorticosteroids, antihistamines, retinoids, less often cytostatic and immunosuppressive drugs. For the purpose of correcting various hormonal disorders in acne, rosacea, menopausal skin aging, use after oral examination with a gynecologist-endocrinologist or endocrinologist, oral contraceptives with anti-androgenic effect, hormone replacement therapy and other drugs. When managing patients, it is important to find out an allergic anamnesis, and when prescribing these or other means of general influence, it is necessary to remember drug interactions (potentially dangerous drug combinations). These include combinations of antihistamines with hypnotics, tranquilizers, sedatives and antipsychotics (aminazine) or a combination of sulfonamides with oral antidiabetic agents, diamino-diphenylsulfone with methotrexate and rifampicin, isotretinoin with vitamin A and tetracycline antibiotics, etc. Glucocorticoid hormones with vaccines, anesthetics and sympathomimetics (adrenaline, ephedrine), and salicylates - with indomethacin, methotrexate, 6-mercaptopurine and oral a with anticoagulants.
In addition to traditional dermatological preparations, vitamins, macro- and microelements, antioxidants, immunomodulators are widely used in cosmetology.
Scientific research and practical experience of recent years have shown the high effectiveness of the means for oral administration, which correspond to the so-called "beauty concept from within". Vitamins A, B1, B2, B6, B12, C, H (biotin), PP and others, as well as macro- and microelements: zinc, calcium, copper, silicon, etc., have the greatest influence on the functional state of the skin, hair, and nails. In this regard, nowadays, combined preparations, including various vitamins and microelements, are quite widely used.
A special role in the aging of the skin, the appearance of its dryness and increased transepidermal water loss is attributed to the deficiency of unsaturated fatty acids in the body. In this regard, for these conditions prescribe drugs that contain omega-fatty acids.
Widely used parapharmaceuticals In particular, it is known that supplementing the standard diet with antioxidants can compensate for the deficiencies in the body's defense against free radicals arising from skin aging.
The antioxidant effect was noted in various groups of drugs: carotyl noids (beta-carotene, lycopene, etc.), flavonoids, ascorbic acid, tocopherol (vitamin E), certain enzymes (superoxide dismutase, catalase, etc.). These drugs are part of a number of combination drugs.
Exogenous melatonin is also used as an antioxidant agent. It is known that this substance in man is produced in the epiphysis - the neuroendocrine organ, which is in close connection with the hypothalamus and peripheral endocrine glands. Therefore, melatonin is also prescribed for the purpose of restoring the circadian system of an aging organism. The drug is recommended to take in the early dark phase of the day, it regulates the disturbed rhythm of sleep - wakefulness.
With an endogenous photoprotective purpose, as well as for the artificial coloration of the skin, drugs including such a lipochrome as carotene are prescribed.
In modern anti-age cosmetology, peptide bioregulators of cytamines are used. Citamins are natural complexes of proteins, nucleic acids, microelements and minerals (copper zinc, magnesium, manganese, iron, phosphorus, potassium, calcium, sodium and other vitamins (thiamine, riboflavin, niacin, retinol acetate, a-tocopherol). In order to activate the synthesis of collagen and elastin, chondramine, vascular bioregulation-vasolomin, liver and pancreas functions-pancramine, and thyroid function are used to stimulate differentiation and function of different cell populations. Eryza - tyramine, suprarenal - supenamine, effective excretion of metabolic products by the urinary system - renisamine The drugs are used in complex therapy for scars, acne, prevention and correction of signs of skin aging Dosage - 2 tablets of each citamine 2-3 times a day for 5 - 10 minutes before meals.
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