Normal articular cartilage performs two main functions: the absorption of pressure by deformation during mechanical stress and ensuring the smoothness of articular surfaces, which allows you to minimize friction when moving in the joint.
Why is the compatibility of Ibuprofen and alcohol impossible, and why is it impossible to drink, say, a shot of vodka at lunch (as they say, "for appetite"), and after eating take a pill? Pay attention to the section "Medicinal and other interactions" in the instructions for the drugs: everything is clearly indicated there.
Natural cytokine inhibitors can directly inhibit the binding of cytokines to the receptors of cell membranes, reducing their pro-inflammatory activity. Natural inhibitors of cytokines can be divided into three classes according to their mode of action.
Thanks to the progress of biotechnology, in particular cloning technology, recently a growing list of growth factors, which, being anabolic factors, play an important but not completely understandable role in the pathogenesis of osteoarthritis.
For the diagnosis of osteoarthritis, various instrumental methods of investigation are currently being used to diagnose osteoarthritis for greater accuracy, assessment of the dynamics of the disease and the effectiveness of treatment: X-rays, arthroscopy, ultrasonography, computed tomography, magnetic resonance imaging (MRI), scintigraphy, thermal imaging.
In recent years, apoplexy has been considered as a method of early diagnosis of osteoarthritis, since it allows one to detect the above changes in cartilage even in the absence of radiographic signs of the disease.
Despite the rapid development in recent years of such modern methods of medical imaging as MRI, X-ray computed tomography, expansion of the possibilities of ultrasound diagnostics, rentegnostic diagnostics of osteoarthritis remains the most common objective method for diagnosing and controlling the effectiveness of osteoarthritis treatment.
Magnetic resonance imaging (MRI) in recent years has become one of the leading methods of non-invasive diagnosis of osteoarthritis. Since the 70s, when the principles of magnetic resonance (MP) were first used to study the human body.
MRI picture of articular cartilage reflects the totality of its histological structure and biochemical composition. Articular cartilage is hyaline, which does not have its own blood supply, lymphatic drainage and innervation. It consists of water and ions, fibers of type II collagen, chondrocytes, aggregated proteoglycans and other glycoproteins.
Bone pathology due to osteoarthrosis includes the formation of osteophytes, subchondral bone sclerosis, the formation of subchondral cysts and bone marrow edema. MRI, due to its multiplanar tomographic capabilities, is more sensitive than radiographic or computed tomography to visualize most of these types of changes.