As a natural component of articular cartilage, glucosamine sulfate (sulfated derivative of natural aminomonosaccharide of glucosamine) was first used as a tool that stimulates reparative processes in patients with osteoarthrosis more than 20 years ago.
The algorithm for treating patients with osteoarthritis has its own peculiarities. If the overwhelming majority of diseases, including non-rheumatic diseases, are preceded by an outpatient or inpatient treatment, then the osteoarthrosis looks different: rehabilitation - outpatient (less often - inpatient) treatment - rehabilitation.
Treatment of osteoarthritis continues to be a serious problem, despite the fact that the list of recently used drugs has significantly increased.
Non-narcotic analgesics (for example, paracetamol) are more often used during the washing period when NSAIDs are approved. However, the results of comparative studies conducted in the 80-90s of the last century indicate that paracetamol may be an alternative to other NSAIDs
The first widely known NSAID was salicylic acid, first synthesized in 1874; soon it was found to be effective in rheumatic fever. In 1875, sodium salicylate was used for the treatment of rheumatic fever for the first time.