Science and Technology

Progression of disability independent of relapse (PIRA), sometimes called “silent progression,” has become a key integrative concept in the modern view of multiple sclerosis (MS).

Scientists have developed a complex procedure that shows promising results when used in combination with these treatments: short laser pulses create sound waves that then provide images of muscle tissue.

Recently, scientists noticed that patients whose tumors have an ARID1A gene mutation are more likely to respond positively to immune checkpoint blockade, a type of immunotherapy that works by keeping cancer-fighting immune cells in an activated state. p>

The team found a subgroup of people who had Alzheimer's disease processes in their brains, but did not show clinical symptoms during their lifetime. This is the so-called “stable” group. But how is it possible that they did not experience any symptoms while others did?