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A new form of coenzyme Q10 could treat male infertility
Last reviewed: 01.07.2025
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Iranian scientists have found that a form of coenzyme Q10 derived from yeast can help men with low sperm motility by improving their kinetic characteristics. Moreover, subsequent analysis showed that the number of pregnancies increased.
Professor Mohammad Reza Safarinejad said: “To evaluate the effectiveness of the coenzyme, clinical trials were conducted using placebo. This made it possible to understand how the compound affects the three sperm properties of density, motility and morphology.”
Coenzyme Q10 functions as a powerful antioxidant, protecting the phospholipid membrane from peroxidation. This enzyme also has the ability to regenerate and reuse other antioxidants, such as tocopherol and ascorbic acid.
During the study, a group of volunteers was recruited and treated for 26 weeks (they were given 300 mg of conezim). This allowed all three parameters mentioned above to be significantly improved. However, in the group that received a placebo, the parameters did not change.
As for pregnancy, a study conducted a little later showed that the treatment guaranteed a pregnancy rate of 34.11 percent in couples where the men were diagnosed with idiopathic male infertility. Moreover, the situation improved even more when the coenzyme was used for more than 6 months.
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