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To lose weight, all you need to do is change your biological rhythm
Last reviewed: 01.07.2025
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The desire to always be slim pushes people to do all sorts of tricks. Hard training in gyms, exhausting diets – all this is done in order not to gain excess weight.
However, American scientists from the Scripps Research Institute in Florida have come to the conclusion that in order to lose weight, it is enough to simply change your biological rhythm. Scientists have managed to synthesize several molecules that have the ability to change a person's biorhythm. Researchers emphasize that a simple change in biorhythm without diets and exercises will help an overweight person lose weight.
The synthesized molecules were able to change the biological clock in the hypothalamus of laboratory mice. This led to a significant decrease in their cholesterol levels. The mice's fat levels decreased without any diet, and the fat mass disappeared on its own.
"Our circadian rhythms are really linked to metabolism, which can be modulated using these molecules," said study author Thomas Burris, a study leader and professor at Scripps Florida.
During the experiments, it was found that the synthetic molecules helped to reduce the level of cholesterol in the blood by 47%. They activated the proteins REV-ERBα and REV-ERBβ, which regulate metabolism: thus, with the same amount of food consumed, the animals were able to lose weight.
The enzymes needed to break down fats and carbohydrates are produced in the human body in different amounts at different times. And a change in the biological clock can reduce the amount of enzymes that break down fats. In this case, fats are simply excreted from the body without being deposited in it and without causing weight gain. A change in the biological rhythm affects the synthesis of the body's own fats, whose speed is also not equal during the day and at night, for example, when the body is resting, the synthesis accelerates.
However, so far scientists have only tested new weight-loss molecules on mice. Researchers claim that the principles of excess weight gain and metabolism in mice and humans are largely similar. If this theory is confirmed, the discovery of American scientists will help advance the treatment of obesity and diabetes.