Scientists have increased the efficiency of artificial insemination
Last reviewed: 23.04.2024
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Australian and Danish scientists have improved the technology of in vitro fertilization (IVF), increasing its efficiency by tens of percent, according to ScienceDaily. It is expected that the improvement will go into clinical practice as early as 2011. Researchers from Adelaide University and the Danish company ORIGIO a / s conducted the largest clinical examination of culture media for embryos obtained as a result of IVF. This work demonstrated the key importance of natural growth factors for the successful implantation of the embryo into the uterus. Based on the results of the study, EmbryoGen contains a granulocyte-macrophage colony-stimulating factor (GM-CSF, GM-CSF). This protein from the group of cytokines ensures the maturation of blood cells in the bone marrow. In addition, it ensures the stability of the embryo to damaging effects in the early implantation period. Clinical trials of EmbryoGen with the participation of 1319 patients undergoing IVF showed that its use improves the success of embryo implantation, registered at the 12th week of development, on average by 20 percent. The cultivation of embryos on this medium proved to be most effective in women whose previous pregnancies were interrupted in the first trimester. In this group of patients, the use of EmbryoGen increased the probability of successful implantation by 40 percent. According to the study manager, Professor Sarah Robertson of Adelaide, the work on improving IVF took 20 years. Scientists expect that, in addition to influencing embryo implantation, EmbryoGen will be able to normalize fetal mass at birth (usually newborns that have appeared with IVF weigh less than naturally conceived). Clinical data confirming or refuting these hopes will be received within a year. It is expected that EmbryoGen will go on sale in 2011.
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