The new method will allow drug development faster
Last reviewed: 23.04.2024
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An international group of scientists from France, America and Russia have developed a new unique way of creating medicines, which differs from the speed that exists to date. Thanks to a new way of modeling interactions between proteins, the process of developing vaccines and medicines can be accelerated, and new potential for research will open up before biochemists.
Now scientists are faced with the task of developing such drugs that would not cause adverse reactions, be fully absorbed by the body and destroy exceptionally unhealthy cells. For the protein cell, the main building material, in one cell there are many interactions (hundreds of thousands), and studying these processes will allow scientists to develop new ways of treating dangerous diseases, create new biological materials for the invention of medications.
Specialists from different countries led by a professor at the University of Stony Brook Dmitry Kozakova were able to create and explore a computer model that can several times calculate the structures formed by the interaction of two proteins (the new model is ten times faster than similar systems that exist today) .
According to scientists, laboratory research is quite expensive, since reagents and expensive equipment are required for their carrying out. For small research groups, the best option is computer simulation. Now there are many computer systems that calculate the interaction between proteins, but, unfortunately, all existing systems are not able to calculate a large number of protein interactions in a short time. All the algorithms currently used monitor the configurations separately, without combining them, and the new method of the team of Professor Kozakov allows you to analyze all the complexes simultaneously in a short time, and this allows you to speed up the process up to 100 times without affecting the quality of the final result.
Taking as a basis a computer model, specialists will be able not only to develop medicines more quickly, but also to significantly reduce their cost. The new method of computer modeling allows not only to calculate protein interactions, but also to analyze the structure of living organisms (both animal and human). According to experts, the new method will allow to develop effective drugs for HIV and cancer, and in a short time it will be possible to prepare a sufficient number of drugs.
The article with the results of the work of the scientists published in one of the scientific journals, in which experts described in detail a new way of computer modeling of protein interactions.
This work is not intended for commercial use, but is a fundamental research, so you can talk about the work done from the moment it appears in the scientific publication. Now the new algorithm is already used on the public server ClusPro as a new computing system and is available to all comers.
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