A mouthwash is developed, which permanently protects against caries
Last reviewed: 23.04.2024
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A new mouthwash developed by microbiologists from the UCLA School of Dentistry (USA) has shown high effectiveness in the treatment of infections caused by the bacterium Streptococcus mutans, which are the main cause of tooth decay.
The clinical study involved 12 people who rinsed the mouth of the experimental fluid once a day. The results of the four-day testing period showed almost complete elimination of S. Mutans.
The results of this small study are published in the current issue of the international dental journal Caries Research.
Dental caries is one of the most common and costly infectious diseases in the US, affecting more than 50% of children and most adults aged 18 and over. Americans spend more than $ 70 billion each year on dental services, with most of this amount going to caries treatment.
A new mouthwash is the product of nearly a decade of research conducted by Dr. V. Shi, chairman of the biology section at the University of California. Shi developed a new technology called "antimicrobial STAMP" (known as C16G2) with the support of Colgate-Palmolive and C3-Jian Inc.
The human body is the "home" for millions of different bacteria, some microorganisms cause diseases, such as dental caries, but many of them are of vital importance to human health. The most common broad-spectrum antibiotics, like ordinary mouthwashes, "indiscriminately" kill both beneficial and pathogenic bacteria.
Abuse of broad-spectrum antibiotics can seriously disrupt the normal ecological balance of the body, which makes people more susceptible to bacterial, yeast (fungal) and parasitic infections.
The investigated medicinal substance Sm Shi STAMP C16G2, acts as a "smart bomb", eliminating only harmful bacteria, remaining effective for a long period.
Based on the success of this clinical study, C3-Jian Inc filed an application with the FDA to begin a broader clinical trial, scheduled for March 2012. If the FDA approves Sm STAMP C16G2 for general use, it will be the first "anti-caries" drug in the world.
"With this new antimicrobial technology, we have the prospect of getting rid of caries for life," said Dr. Shi.
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