Medical expert of the article
New publications
A drug has been developed that prevents prostate cancer from metastasizing
Last reviewed: 01.07.2025

All iLive content is medically reviewed or fact checked to ensure as much factual accuracy as possible.
We have strict sourcing guidelines and only link to reputable media sites, academic research institutions and, whenever possible, medically peer reviewed studies. Note that the numbers in parentheses ([1], [2], etc.) are clickable links to these studies.
If you feel that any of our content is inaccurate, out-of-date, or otherwise questionable, please select it and press Ctrl + Enter.
Scientists from the United States have developed a drug that prevents the spread of metastases in prostate cancer. As reported by EurekAlert!, Li Xu, an employee of Northwestern University in Chicago, spoke about the development at the annual conference of the American Association for Cancer Research (AACR).
The research team conducted a series of experiments on laboratory mice. They transplanted malignant cells taken from patients with prostate cancer into the animals. The rodents were given the experimental drug KBU2046 for five weeks.
The control mice developed lung cancer metastases, indicating the spread of malignant cells, while no metastases were found in the KBU2046-treated mice. In addition, the results of experiments on human malignant cell cultures showed that the experimental drug was not toxic.
According to the researchers, malignant cells have proteins that trigger their aggressive spread. KBU2046 binds to these proteins and deactivates them. The scientists expressed hope that the results of the study will be confirmed during clinical trials of the drug.