Lumbar spinal stenosis (PSS), being well determined from the morphological point of view, is heterogeneous in clinical manifestations. Polymorphism of clinical syndromes in patients with lumbar spinal stenosis suggests diffuse morphological changes in the structures of the spinal canal and their ambiguity.
The first detailed clinical description of scoliosis belongs to Ambroise Paré, who also outlined the basic principles of treating scoliosis with an iron device. At the same time, as some authors point out, this disease was also known to Hippocrates, who used wooden tires to correct deformations of the spine.
The agent can be prescribed for spasms in the muscles, to relieve swelling and inflammation, as well as restore the function of the nerve root.
Ointments, gels, creams and balms are the most popular means of external application.
Antilepressant (tricyclic antidepressant). It also has some analgesic (central genesis), H2-histamine-blocking and antiserotonin action, contributes to the elimination of urinary incontinence and reduces appetite.
Antiepileptic agent (dibenzazepine derivative), which also has a normotimic, antimanic, antidiuretic (in patients with diabetes insipidus) and analgesic (in patients with neuralgia).
Miorelaxant of central action, a derivative of gamma-aminobutyric acid (GABAb-stimulant). Reducing the excitability of the end sections of the afferent sensitive fibers and suppressing the intermediate neurons, inhibits the mono- and polysynaptic transmission of nerve impulses; reduces the preliminary stress of the muscle spindles. Has no effect on neuromuscular transmission.
Has antiarrhythmic (lb class) properties. Stabilizes cell membranes, blocks sodium channels, increases membrane permeability for K +. Almost without affecting the electrophysiological state of the atrium, accelerates repolarization in the ventricles, inhibits the depolarization phase IV in the Purkinje fibers
Narcotic analgesic, an agonist of opiate receptors (mainly mu-receptors) of the central nervous system, spinal cord and peripheral tissues. Increases the activity of the antinociceptive system, increases the threshold of pain sensitivity.
NSAID, a phenylacetic acid derivative; has anti-inflammatory, analgesic and antipyretic effects associated with indiscriminate suppression of COX1 and COX2, regulating the synthesis of Pg.