Scientists have found a way how to restore youth

Specialists have found out how to reverse the aging process of cells. So far, experiments have been conducted on laboratory mice, but scientists believe that this discovery can significantly help in the treatment of serious diseases, such as malignancies, diabetes mellitus and degenerative diseases of the nervous system, as well as in studying other diseases associated with age-related changes. As a result, the conducted studies showed that when the number of NAD + molecules decreases, a disruption of the connection between mitochondrial and nuclear gene cells occurs, which promotes accelerated aging. After the introduction of experimental animals in old age NAD +, scientists noted the restoration of normal mitochondrial work in the body, while experts established that according to biological characteristics, the age of animals approached a younger one.

Each cell of the body is fed with energy, obtained through a biochemical reaction, which occurs during the oxidation of nutrients supplied with food. During this, energy is released, which is deposited in the form of ATP molecules. This process has the name of cellular respiration and it proceeds in the mitochondria possessing their own DNA. Together with nuclear cells, mitochondria encode some components that participate in the process of respiration of cells. The active work of mitochondria decreases with age, often it is associated with diabetes or Alzheimer's disease.

A group of researchers, led by David Sinclair, conducted animal studies, where sirtuin protein SIRT1 was suppressed, an increased amount of which slows down the aging of cells. As experts suggested, the mice had to activate the aging process associated with a violation of the functions of nuclear and mitochondrial cells. But, the results of the experiments turned out to be slightly different: most of the proteins encoded by nuclear genes were normal. Reduction was observed only in those proteins, for the encoding of which met the mitochondria.

As the project manager noted, the high level of SIRT1 allows both gene cells to work together, which also prevents aging of cells. With age, the amount of NAD + in the body decreases, as a result of which SIRT1 loses its ability to influence the aging processes. After such results, the researchers decided to determine whether there is a probability of preventing the aging process if the SIRT1 level is increased due to an increase in the level of NAD +.

The experiment lasted one week, during which scientists twice daily administered to mice, whose age was about two years, the molecules of nicotinamide mononucleotide (preceding NAD +). The specialists determined that the age of the mouse tissues by biological parameters approached the six-month period, muscular atrophies and inflammations decreased. If we translate into human age, this means that the organism of a 64-year-old person would become an 18-year-old.

Specialists note that they are only at the initial stage of work, and in the future it is necessary to conduct a lot of research. But if all the results are confirmed, some aging processes can be reversed, provided that they are captured early enough.

Now, scientists are studying the results of using NAD + compounds (in particular nicotinamide mononucleotide) and how they affect the health and longevity of experimental animals. In the near future, they intend to study the safety of using such therapy for cancer and type I and II diabetes.

Let's remind about the recent statement of scientists about the fact that the violation of biological rhythms leads to premature aging of the skin.

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