Skinoren

Skinoren (azelaic acid) is a medication that is widely used to treat a variety of skin problems, especially acne (acne) and rosacea. Azelaic acid, the main active ingredient in Skinoren, has a number of benefits for the skin:

1. Antibacterial Action: Azelaic acid helps to reduce the number of bacteria that can cause acne. It effectively fights the bacteria Propionibacterium acnes, which is often associated with the development of acne.
2. Anti-inflammatory: Skinoren reduces inflammation in the skin, which helps reduce the redness and irritation associated with acne and rosacea.
3. Reduce sebumproduction: Azelaic acid can help reduce sebum production, which reduces the risk of clogged pores and acne.
4. Exfoliation: The product helpsexfoliate keratinized skin cells, improving skin texture and reducing the likelihood of clogged pores.
5. Pigmentation Reduction: Azelaic acid can help reduce hyperpigmentation and age spots associated with acne, post-acne and other skin problems.

Skinorin is usually available as a gel or cream for external use. It is applied to clean and dry skin once or twice a day, depending on your doctor's recommendations. Results usually become noticeable after a few weeks of regular use. As with any other medical product, it is recommended that you consult your doctor before starting to use Skinoren.

Indications Skynorrhea

1. Acne (acne): Skinoren is effective in treating various forms of acne, including blackheads, black spots, and inflamed papules and pustules. It helps to reduce the amount of acne, reduce inflammation and prevent new rashes from forming.
2. Rosacea: This drug is also indicated in the treatment of rosacea, a chronic skin disorder characterized by redness, inflammation and flushing of the facial skin, and the appearance of red papules and pustules.
3. Hyperpigmentation: Skinoren can help reduce hyperpigmentation, including age spots and post-acne, due to its property of reducing melanin production in the skin.
4. Post-acne: After acne disappears, spots or scars on the skin are often left behind. Skinoren can help reduce their appearance and speed up the healing process.
5. Keratosis: This medicine may also be used to treat keratoses (rough patches of skin) on the face and body.

Release form

Skinoren, containing the active ingredient azelaic acid, is available in two main forms of release for external use:

1. Cream

Skinoren cream usually contains 20% azelaic acid. This form is suitable for treating acne (acne) and rosacea. The cream has a consistency that is well absorbed by the skin, making it suitable for normal to dry skin.

2. Gel

Skinoren gel usually contains 15% azelaic acid and is recommended for treating the same conditions as the cream. The gel is lighter than a cream and may be preferred for oily skin because it is less greasy and absorbs more quickly.

Pharmacodynamics

1. Antibacterial action: Azelaic acid is active against bacteria such as Propionibacterium acnes, which play a role in the development of acne. This antibacterial action helps to reduce acne and reduce skin inflammation.
2. Keratolytic action: The product promotes exfoliation ofkeratinized skin cells, which helps prevent the formation of comedones and reduces the risk of inflammatory elements.
3. Anticomedogenic action: Azelaic acid helps to reduce sebum production, which helps to reduce the size and number of comedones.
4. Antioxidant Action: Azelaic acid has antioxidant properties that help protect the skin from free radicals and prevent skin cell damage.

Pharmacokinetics

Since azelaic acid is mainly applied topically, its systemic exposure and pharmacokinetics in the blood remain minimal. It is usually not absorbed in significant amounts through the skin and has no systemic effects on the body. Its main mechanism of action is to reduce the number of bacteria in skin pores, reduce inflammation and regulate skin keratinization.

Dosing and administration

Method of Application:

1. Skin cleansing: Before applying Skinoren, the skin should be thoroughly cleaned with a mild cleanser and dried. This will help to maximize the effectiveness of the treatment.
2. Application: Apply a small amount of cream or gel to affected skin areas in a thin layer. Avoid contact with the mucous membranes of the eyes, mouth and nose.
3. Frequency of use: Skinoren is usually applied to the skin 2 times a day (morning and evening), unless otherwise prescribed by a doctor.

Dosage:

• As a rule, applying a thin layer of the drug to the affected areas of the skin is sufficient for effective treatment. The exact amount depends on the size of the area to be treated.

Additional tips:

• Use of sunscreen: During and after treatment with Skinoren, the skin may become more sensitive to sunlight. It is recommended to use a sunscreen with a high SPF to protect the skin from UV rays.
• Duration of treatment: Skin improvement with Skinoren is usually noticeable after 4-6 weeks of regular use, but the course of treatment may need to be extended to several months to maximize the effect.
• Interaction with other skin products: Avoid simultaneous use of Skinoren with other topical preparations, especially those that cause dryness or irritation of the skin, without consulting your doctor.

Use Skynorrhea during pregnancy

Currently, there is limited data on the safety of azelaic acid (Skinoren) use during pregnancy. Therefore, it is recommended to consult a doctor before starting to use this drug during pregnancy.

Contraindications

1. Hypersensitivity: People with known hypersensitivity to azelaic acid or any other component of the product should not use Skinoren because of the risk of allergic reactions.
2. Known allergic reactions to other acids: Because Skinoren contains acid, patients who have known allergic reactions to other acids, such as glycolic acid or salicylic acid, may be at an increased risk of developing allergic reactions.
3. Confirmed or suspected fullicular acne: According to some reports, the use of azelaic acid may aggravate the condition of fullicular acne, so the use of Skinoren may not be desirable in such cases.
4. Pregnancy and breastfeeding: There is limited data on the safety of azelaic acid use during pregnancy and breastfeeding, so it is recommended to consult a physician before use in such cases.
5. Children: The safety and efficacy of Skinoren in children have not been established, therefore its use in children should be carried out under the supervision of a doctor.
6. Skincondition: Skinoren may cause skin irritation and aggravate the condition in the presence of acute inflammatory or wound processes on the skin. In such cases, the use of the drug may be undesirable.

Side effects Skynorrhea

Cutaneous reactions:

• Skin redness, irritation and burning: The most common side effects, especially at the beginning of treatment. These symptoms are usually mild to moderate and decrease over time as the skin adapts to the drug.
• Dry and flaky skin: May occur in the area of application, especially if the skin already tends to be dry.
• Itching: Some patients may experience mild itching after applying the ointment or gel.
• Hyperpigmentation: Rarely, but an increase in pigmentation on the skin may occur, especially in individuals with darker skin color.

Rare side effects:

• Allergic Reactions: Very rarely, allergic reactions including hives, facial swelling or difficulty breathing may occur. If signs of an allergic reaction occur, you should stop using Skinoren immediately and consult a doctor.

It's important to know:

• Side effects are generally temporary and usually diminish as treatment continues.
• If severe skin irritation or other severe side effects occur, a doctor should be consulted, as dosage adjustment or discontinuation of the drug may be required.
• To minimize the risk of side effects, it is important to strictly follow the recommendations for use specified by the doctor and in the instructions for the drug, including the frequency and method of application.

Overdose

Overdose of Skinoren is unlikely due to its topical application. However, if a large dose is swallowed or applied to large areas of skin, skin irritation, tingling or burning, and blistering may occur.

Interactions with other drugs

Interactions between azelaic acid, the main active ingredient in Skinoren, and other drugs are largely unstudied due to the fact that azelaic acid is usually used topically to treat skin conditions. Such topical preparations rarely cause systemic interactions with other drugs.