Prognosis of pancreatic head cancer

, medical expert
Last reviewed: 11.04.2020

All iLive content is medically reviewed or fact checked to ensure as much factual accuracy as possible.

We have strict sourcing guidelines and only link to reputable media sites, academic research institutions and, whenever possible, medically peer reviewed studies. Note that the numbers in parentheses ([1], [2], etc.) are clickable links to these studies.

If you feel that any of our content is inaccurate, out-of-date, or otherwise questionable, please select it and press Ctrl + Enter.

The prognosis for pancreatic cancer is unfavorable. After the imposition of biliodigestive anastomosis, the average survival is about 6 months. The prognosis for acinar-cell cancer is worse than in the case of protocol, because the regional lymph nodes are affected earlier. The tumor is resectable only in 5-20% of patients.

Mortality after radical surgery is 15-20%, but recently it has been possible to reduce it to 5% in specialized centers where much more operations are performed and surgeons have a lot of experience. In a recent report from one specialized center after 145 pancreatoduodenal resections, there were no lethal outcomes. However, this is an exceptional case.

Parallel to the reduction in postoperative mortality, the five-year survival rate increased to 20%. Perhaps this reflects an earlier diagnosis due to the use of modern visualization methods of research or is a consequence of the selection for surgery of patients with less common lesions. However, the problem of combating tumor recurrence is still not solved. Total pancreatectomy does not allow to achieve a longer life expectancy compared with a smaller pancreatoduodenal resection by Whipple and causes deficiency of the exocrine function of the gland and severe diabetes.

In general, the prospects for pancreatic cancer are unfavorable: in one study of 912 patients in 3 years 23 were alive and only 2 patients could be considered cured.

The prognosis for cancer of the ampulla is more favorable, the five-year survival after radical surgery with a tumor that does not spread beyond the sphincter of Oddi was 85%, and with more severe invasion - 11-25%. The method of choice is pancreatoduodenal resection. In some cases, local excision of the tumor can be performed.

trusted-source[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14]

You are reporting a typo in the following text:
Simply click the "Send typo report" button to complete the report. You can also include a comment.