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Cronckheit-Canada Syndrome
Last reviewed: 17.10.2021
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[Symptoms of Cronkhet syndrome - Canada
This syndrome is a complex of congenital anomalies: generalized polyposis of the gastrointestinal tract (including duodenum and stomach), atrophy of nails, alopecia, cutaneous hyperpigmentation, sometimes in combination with exudative enteropathy, insufficiency syndrome, hypocalcemia, potassium and magnesium. It is known that the main source of protein loss (albumins) in this syndrome is the affected stomach, the protein is lost due to increased production of gastric mucus and multiple surface necrosis of polyps. With this syndrome, cystic enlargement of glands in polyps is possible. There are also some other rare forms of hereditary and non-hereditary common polyposis of the digestive tract, the nosological independence of which has not yet been established. In any case, patients with polyposis of the stomach and duodenum or large intestine need to examine the entire gastrointestinal tract (aim X-ray examination, fibroendoscopy) in order not to miss one of the forms of a common polyposis of the entire digestive tract. Patients with multiple polyposis of the duodenum (and the entire digestive tract) in those cases where polyps are not shown or can not be removed should be on dispensary supervision with the oncologist.
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Treatment of Cronkhai syndrome - Canada
Therapeutic tactics are determined by the prevalence of polyposis, the size of polyps, the presence or absence of complications. Large polyps are to be removed. The possibility of providing medical treatment to patients has been significantly expanded with the introduction of endoscopic polypectomy, carried out in various ways - using electrocoagulation, laser radiation, a special loop for removal of polyps, biopsy forceps, etc. The occurrence of complications - acute gastrointestinal bleeding, intestinal obstruction - is an indication to urgent surgical intervention. Malignant polyps also require surgical treatment.