^

Scarring of the skin

Stages and course of the wound process

Speaking of local reactions, various authors agree that it is necessary to distinguish 3 main stages of the wound process. So Chernuk AM (1979) distinguished the stage of damage, the stage of inflammation and the stage of recovery.

Neurohumoral reactions underlying reparative processes in skin injuries

It is known that the skin is a multifunctional organ that performs respiratory, nutritional, thermoregulatory, detoxifying, excretory, barrier-protective, vitamin-forming and other functions.

Stria

Striae is an absolutely independent nosology in terms of etiopathogenesis, both in terms of clinical and morphological picture, and in terms of treatment.

Hypertrophic scars: causes, symptoms, diagnosis, treatment

Hypertrophic scars often combine a group of pathological scars in common with keloid scars in connection with that. That both species are characterized by excessive formation of fibrous tissue and arise as a result of prolonged inflammation, hypoxia, attachment of secondary infection, reduction of local immunological reactions. In a history of such patients, endocrinopathies are sometimes found.

Keloid scars: causes, symptoms, diagnosis, treatment

The name keloid comes from the Greek word keleis - tumor and eidos-type, similarity. Keloids are divided into two groups - true or spontaneous and cicatricial or false.

Scars resulting from an adequate pathophysiological skin reaction

Depending on the location and depth of destructive changes, scars can have different clinical manifestations. So the scar, located flush with the skin, not causing deformation of the skin and underlying tissues is called normotrophic.

The main functional units of the skin involved in the healing of a skin defect and scarring

Basal keratinocyte is not only the mother cell of the epidermis, which gives rise to all overlying cells, but is a mobile and powerful bioenergetic system.

The mechanisms underlying the formation of keloid and hypertrophic scars

The lack of any components necessary for the implementation of "protective", physiological inflammation, can prolong this process and transfer it to an "inadequate" level.

The mechanisms underlying the scar formation of Group 1

In response to trauma with damage to the vasculature, the skin develops an inflammatory process, which is a natural protective reaction of the body. The purpose of the inflammatory reaction is to remove fragments of the destroyed skin and, ultimately, to close the skin defect with a newly formed tissue in order to maintain homeostasis.

Ways of skin regeneration

In response to damage to the skin, neuro-humoral mechanisms come into play that aim to restore the body's homeostasis through the closure of a wound defect. And the faster is the restoration of the integrity of the skin (there is epithelization of the wound), the greater the likelihood of obtaining either an abruptly healing or healing with the formation of aesthetically acceptable scars.

Pages

You are reporting a typo in the following text:
Simply click the "Send typo report" button to complete the report. You can also include a comment.